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Transcriptional Regulation of Human and Rat Hepatic Lipid Metabolism by the Grapefruit Flavonoid Naringenin: Role of PPARα, PPARγ and LXRα

Disruption of lipid and carbohydrate homeostasis is an important factor in the development of prevalent metabolic diseases such as diabetes, obesity, and atherosclerosis. Therefore, small molecules that could reduce insulin dependence and regulate dyslipidemia could have a dramatic effect on public...

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Detalhes bibliográficos
Main Authors: Goldwasser, Jonathan, Cohen, Pazit Y., Yang, Eric, Balaguer, Patrick, Yarmush, Martin L., Nahmias, Yaakov
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928300/
https://ncbi.nlm.nih.gov/pubmed/20811644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012399
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