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The macrophage LBP gene is an LXR target that promotes macrophage survival and atherosclerosis

The liver X receptors (LXRs) are members of the nuclear receptor superfamily that regulate sterol metabolism and inflammation. We sought to identify previously unknown genes regulated by LXRs in macrophages and to determine their contribution to atherogenesis. Here we characterize a novel LXR target...

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Detaylı Bibliyografya
Asıl Yazarlar: Sallam, Tamer, Ito, Ayaka, Rong, Xin, Kim, Jason, van Stijn, Caroline, Chamberlain, Brian T., Jung, Michael E., Chao, Lily C., Jones, Marius, Gilliland, Thomas, Wu, XiaoHui, Su, Grace L., Tangirala, Rajendra K., Tontonoz, Peter, Hong, Cynthia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Biochemistry and Molecular Biology 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031943/
https://ncbi.nlm.nih.gov/pubmed/24671012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M047548
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