The macrophage LBP gene is an LXR target that promotes macrophage survival and atherosclerosis

The liver X receptors (LXRs) are members of the nuclear receptor superfamily that regulate sterol metabolism and inflammation. We sought to identify previously unknown genes regulated by LXRs in macrophages and to determine their contribution to atherogenesis. Here we characterize a novel LXR target...

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Detalhes bibliográficos
Main Authors: Sallam, Tamer, Ito, Ayaka, Rong, Xin, Kim, Jason, van Stijn, Caroline, Chamberlain, Brian T., Jung, Michael E., Chao, Lily C., Jones, Marius, Gilliland, Thomas, Wu, XiaoHui, Su, Grace L., Tangirala, Rajendra K., Tontonoz, Peter, Hong, Cynthia
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031943/
https://ncbi.nlm.nih.gov/pubmed/24671012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M047548
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