The macrophage LBP gene is an LXR target that promotes macrophage survival and atherosclerosis

The liver X receptors (LXRs) are members of the nuclear receptor superfamily that regulate sterol metabolism and inflammation. We sought to identify previously unknown genes regulated by LXRs in macrophages and to determine their contribution to atherogenesis. Here we characterize a novel LXR target...

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Detalles Bibliográficos
Autores principales: Sallam, Tamer, Ito, Ayaka, Rong, Xin, Kim, Jason, van Stijn, Caroline, Chamberlain, Brian T., Jung, Michael E., Chao, Lily C., Jones, Marius, Gilliland, Thomas, Wu, XiaoHui, Su, Grace L., Tangirala, Rajendra K., Tontonoz, Peter, Hong, Cynthia
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2014
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031943/
https://ncbi.nlm.nih.gov/pubmed/24671012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M047548
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