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Modulation of the Kinesin ATPase Cycle by Neck Linker Docking and Microtubule Binding

Kinesin motor proteins use an ATP hydrolysis cycle to perform various functions in eukaryotic cells. Many questions remain about how the kinesin mechanochemical ATPase cycle is fine-tuned for specific work outputs. In this study, we use isothermal titration calorimetry and stopped-flow fluorometry t...

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Detalles Bibliográficos
Main Authors: Zhao, Yu Cheng, Kull, F. Jon, Cochran, Jared C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919084/
https://ncbi.nlm.nih.gov/pubmed/20558732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.123067
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