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Modulation of the Kinesin ATPase Cycle by Neck Linker Docking and Microtubule Binding

Kinesin motor proteins use an ATP hydrolysis cycle to perform various functions in eukaryotic cells. Many questions remain about how the kinesin mechanochemical ATPase cycle is fine-tuned for specific work outputs. In this study, we use isothermal titration calorimetry and stopped-flow fluorometry t...

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Bibliographic Details
Main Authors: Zhao, Yu Cheng, Kull, F. Jon, Cochran, Jared C.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919084/
https://ncbi.nlm.nih.gov/pubmed/20558732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.123067
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