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Neck-Linker Docking Coordinates the Kinetics of Kinesin's Heads

Conventional kinesin is a two-headed homodimeric motor protein, which is able to walk along microtubules processively by hydrolyzing ATP. Its neck linkers, which connect the two motor domains and can undergo a docking/undocking transition, are widely believed to play the key role in the coordination...

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Autori principali: Czövek, András, Szöllősi, Gergely J., Derényi, Imre
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3072627/
https://ncbi.nlm.nih.gov/pubmed/21463586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.01.039
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