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The ATPase Cycle of the Nonmotile Kinesin NOD Allows Microtubule Plus-End Tracking and Drives Chromosome Movement
Segregation of nonexchange chromosomes during Drosophila melanogaster meiosis requires the proper function of NOD, a nonmotile Kinesin-10. We have determined the X-ray crystal structure of the NOD catalytic domain in the ADP- and AMPPNP-bound states. These structures reveal an alternate conformation...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2635066/ https://ncbi.nlm.nih.gov/pubmed/19135893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.11.048 |
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