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The Use of Divalent Metal Ions by Type II Topoisomerases

Type II topoisomerases are essential enzymes that regulate DNA under- and overwinding and remove knots and tangles from the genetic material. In order to carry out their critical physiological functions, these enzymes utilize a double-stranded DNA passage mechanism that requires them to generate a t...

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Detalhes bibliográficos
Main Authors: Deweese, Joseph E., Osheroff, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918885/
https://ncbi.nlm.nih.gov/pubmed/20703329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c003759a
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