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The Osteogenic Transcription Factor Runx2 Regulates Components of the Fibroblast Growth Factor/Proteoglycan Signaling Axis in Osteoblasts

Heparan sulfate proteoglycans cooperate with basic Fibroblast Growth Factor (bFGF/FGF2) signaling to control osteoblast growth and differentiation, as well as metabolic functions of osteoblasts. FGF2 signaling modulates the expression and activity of Runt-related transcription factor 2 (Runx2/Cbfa1)...

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Bibliografiske detaljer
Main Authors: Teplyuk, Nadiya M., Haupt, Larisa M., Ling, Ling, Dombrowski, Christian, Mun, Foong Kin, Nathan, Saminathan S., Lian, Jane B., Stein, Janet L., Stein, Gary S., Cool, Simon M., van Wijnen, Andre J.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918404/
https://ncbi.nlm.nih.gov/pubmed/19259985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22108
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