The Osteogenic Transcription Factor Runx2 Controls Genes Involved in Sterol/Steroid Metabolism, Including Cyp11a1 in Osteoblasts

Steroid hormones including (1,25)-dihydroxyvitamin D3, estrogens, and glucocorticoids control bone development and homeostasis. We show here that the osteogenic transcription factor Runx2 controls genes involved in sterol/steroid metabolism, including Cyp11a1, Cyp39a1, Cyp51, Lss, and Dhcr7 in murin...

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Autori principali: Teplyuk, Nadiya M., Zhang, Ying, Lou, Yang, Hawse, John R., Hassan, Mohammad Q., Teplyuk, Viktor I., Pratap, Jitesh, Galindo, Mario, Stein, Janet L., Stein, Gary S., Lian, Jane B., van Wijnen, Andre J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Endocrine Society 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691677/
https://ncbi.nlm.nih.gov/pubmed/19342447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2008-0270
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