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Structural Coupling of Smad and Runx2 for Execution of the BMP2 Osteogenic Signal
Two regulatory pathways, bone morphogenetic protein (BMP)/transforming growth factor-β (TGFβ) and the transcription factor RUNX2, are required for bone formation in vivo. Here we show the interdependent requirement of these pathways to induce an osteogenic program. A panel of Runx2 deletion and poin...
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| Hoofdauteurs: | , , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Biochemistry and Molecular Biology
2008
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2417186/ https://ncbi.nlm.nih.gov/pubmed/18204048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M705578200 |
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