A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2

Lineage progression in osteoblasts and chondrocytes is stringently controlled by the cell-fate–determining transcription factor Runx2. In this study, we directly addressed whether microRNAs (miRNAs) can control the osteogenic activity of Runx2 and affect osteoblast maturation. A panel of 11 Runx2-ta...

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Bibliografiske detaljer
Main Authors: Zhang, Ying, Xie, Rong-lin, Croce, Carlo M., Stein, Janet L., Lian, Jane B., van Wijnen, Andre J., Stein, Gary S.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2011
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116419/
https://ncbi.nlm.nih.gov/pubmed/21628588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018493108
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