Control of Mesenchymal Lineage Progression by MicroRNAs Targeting Skeletal Gene Regulators Trps1 and Runx2

Multiple microRNAs (miRNAs) that target the osteogenic Runt-related transcription factor 2 (RUNX2) define an interrelated network of miRNAs that control osteoblastogenesis. We addressed whether these miRNAs have functional targets beyond RUNX2 that coregulate skeletal development. Here, we find that...

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Detalhes bibliográficos
Main Authors: Zhang, Ying, Xie, Rong-lin, Gordon, Jonathan, LeBlanc, Kimberly, Stein, Janet L., Lian, Jane B., van Wijnen, Andre J., Stein, Gary S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381153/
https://ncbi.nlm.nih.gov/pubmed/22544738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.340398
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