Production of infectious hepatitis C virus in tissue culture from a cloned viral genome

Hepatitis C virus (HCV) infection causes chronic liver diseases and is a global public health problem. Detailed analyses of HCV have been hampered by the lack of viral culture systems. Subgenomic replicons of the JFH1 genotype 2a strain cloned from an individual with fulminant hepatitis replicate ef...

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Detalhes bibliográficos
Main Authors: Wakita, Takaji, Pietschmann, Thomas, Kato, Takanobu, Date, Tomoko, Miyamoto, Michiko, Zhao, Zijiang, Murthy, Krishna, Habermann, Anja, Kräusslich, Hans-Georg, Mizokami, Masashi, Bartenschlager, Ralf, Liang, T Jake
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918402/
https://ncbi.nlm.nih.gov/pubmed/15951748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1268
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