Production of infectious hepatitis C virus in tissue culture from a cloned viral genome

Hepatitis C virus (HCV) infection causes chronic liver diseases and is a global public health problem. Detailed analyses of HCV have been hampered by the lack of viral culture systems. Subgenomic replicons of the JFH1 genotype 2a strain cloned from an individual with fulminant hepatitis replicate ef...

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Autori principali: Wakita, Takaji, Pietschmann, Thomas, Kato, Takanobu, Date, Tomoko, Miyamoto, Michiko, Zhao, Zijiang, Murthy, Krishna, Habermann, Anja, Kräusslich, Hans-Georg, Mizokami, Masashi, Bartenschlager, Ralf, Liang, T Jake
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2005
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918402/
https://ncbi.nlm.nih.gov/pubmed/15951748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1268
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