Production of Infectious Chimeric Hepatitis C Virus Genotype 2b Harboring Minimal Regions of JFH-1

To establish a cell culture system for chimeric hepatitis C virus (HCV) genotype 2b, we prepared a chimeric construct harboring the 5′ untranslated region (UTR) to the E2 region of the MA strain (genotype 2b) and the region of p7 to the 3′ UTR of the JFH-1 strain (genotype 2a). This chimeric RNA (MA...

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Autori principali: Murayama, Asako, Kato, Takanobu, Akazawa, Daisuke, Sugiyama, Nao, Date, Tomoko, Masaki, Takahiro, Nakamoto, Shingo, Tanaka, Yasuhito, Mizokami, Masashi, Yokosuka, Osamu, Nomoto, Akio, Wakita, Takaji
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
Soggetti:
Genome Replication and Regulation of Viral Gene Expression
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302416/
https://ncbi.nlm.nih.gov/pubmed/22156532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05386-11
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