STAT3 is constitutively phosphorylated on serine 727 residues, binds DNA, and activates transcription in CLL cells

Chronic lymphocytic leukemia (CLL) is the most common leukemia in the Western hemisphere, but its pathogenesis is still poorly understood. Constitutive tyrosine phosphorylation (p) of signal transducer and activator of transcription (STAT) 3 occurs in several solid tumors and hematologic malignancie...

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Bibliographische Detailangaben
Hauptverfasser: Hazan-Halevy, Inbal, Harris, David, Liu, Zhiming, Liu, Jie, Li, Ping, Chen, Xiaomin, Shanker, Sreejesh, Ferrajoli, Alessandra, Keating, Michael J., Estrov, Zeev
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2010
Schlagworte:
Lymphoid Neoplasia
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918366/
https://ncbi.nlm.nih.gov/pubmed/20154216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-10-230060
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