STAT3 is constitutively phosphorylated on serine 727 residues, binds DNA, and activates transcription in CLL cells

Chronic lymphocytic leukemia (CLL) is the most common leukemia in the Western hemisphere, but its pathogenesis is still poorly understood. Constitutive tyrosine phosphorylation (p) of signal transducer and activator of transcription (STAT) 3 occurs in several solid tumors and hematologic malignancie...

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Detalhes bibliográficos
Main Authors: Hazan-Halevy, Inbal, Harris, David, Liu, Zhiming, Liu, Jie, Li, Ping, Chen, Xiaomin, Shanker, Sreejesh, Ferrajoli, Alessandra, Keating, Michael J., Estrov, Zeev
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918366/
https://ncbi.nlm.nih.gov/pubmed/20154216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-10-230060
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