Stimulation of the B-cell receptor activates the JAK2/STAT3 signaling pathway in chronic lymphocytic leukemia cells

In chronic lymphocytic leukemia (CLL), stimulation of the B-cell receptor (BCR) triggers survival signals. Because in various cells activation of the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway provides cells with survival advantage, we wondered whether BCR sti...

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Autori principali: Rozovski, Uri, Wu, Ji Yuan, Harris, David M., Liu, Zhiming, Li, Ping, Hazan-Halevy, Inbal, Ferrajoli, Alessandra, Burger, Jan A., O’Brien, Susan, Jain, Nitin, Verstovsek, Srdan, Wierda, William G., Keating, Michael J., Estrov, Zeev
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2014
Soggetti:
Lymphoid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055926/
https://ncbi.nlm.nih.gov/pubmed/24778152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-10-534073
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