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At high levels, constitutively activated STAT3 induces apoptosis of CLL cells

In chronic lymphocytic leukemia (CLL) the increment in peripheral blood lymphocytes is slower than the expected increment calculated from the cells’ proliferation rate, suggesting that cellular proliferation and apoptosis are concurrent. Exploring this phenomenon, we found overexpression of caspase3...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Rozovski, Uri, Harris, David M., Li, Ping, Liu, Zhiming, Wu, Ji Yuan, Grgurevic, Srdana, Faderl, Stefan, Ferrajoli, Alessandra, Wierda, William G., Martinez, Matthew, Verstovsek, Srdan, Keating, Michael J., Estrov, Zeev
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868805/
https://ncbi.nlm.nih.gov/pubmed/27076684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402108
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