At high levels, constitutively activated STAT3 induces apoptosis of CLL cells

In chronic lymphocytic leukemia (CLL) the increment in peripheral blood lymphocytes is slower than the expected increment calculated from the cells’ proliferation rate, suggesting that cellular proliferation and apoptosis are concurrent. Exploring this phenomenon, we found overexpression of caspase3...

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Publicat a:J Immunol
Autors principals: Rozovski, Uri, Harris, David M., Li, Ping, Liu, Zhiming, Wu, Ji Yuan, Grgurevic, Srdana, Faderl, Stefan, Ferrajoli, Alessandra, Wierda, William G., Martinez, Matthew, Verstovsek, Srdan, Keating, Michael J., Estrov, Zeev
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868805/
https://ncbi.nlm.nih.gov/pubmed/27076684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402108
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