At high levels, constitutively activated STAT3 induces apoptosis of CLL cells

In chronic lymphocytic leukemia (CLL) the increment in peripheral blood lymphocytes is slower than the expected increment calculated from the cells’ proliferation rate, suggesting that cellular proliferation and apoptosis are concurrent. Exploring this phenomenon, we found overexpression of caspase3...

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發表在:J Immunol
Main Authors: Rozovski, Uri, Harris, David M., Li, Ping, Liu, Zhiming, Wu, Ji Yuan, Grgurevic, Srdana, Faderl, Stefan, Ferrajoli, Alessandra, Wierda, William G., Martinez, Matthew, Verstovsek, Srdan, Keating, Michael J., Estrov, Zeev
格式: Artigo
語言:Inglês
出版: 2016
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868805/
https://ncbi.nlm.nih.gov/pubmed/27076684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402108
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