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Discontinuous movement and conformational change during pausing and termination by T7 RNA polymerase

Time-resolved characterization of T7 RNA polymerase pausing and terminating at a class II termination site has been carried out using site-specifically tethered chemical nucleases. The data indicate that T7RNAP normally moves uniformly down the template as a rigid body. However, at the class II site...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mukherjee, Srabani, Brieba, Luis G., Sousa, Rui
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC291813/
https://ncbi.nlm.nih.gov/pubmed/14657021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg618
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