RNA polymerase accommodates a pause RNA hairpin by global conformational rearrangements that prolong pausing

Sequence-specific pausing by RNA polymerase (RNAP) during transcription plays crucial and diverse roles in gene expression. In bacteria, RNA structures are thought to fold within the RNA exit channel of the RNAP and can increase pause lifetimes significantly. The biophysical mechanism of pausing is...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell
Egile Nagusiak: Kang, Jin Young, Mishanina, Tatiana V., Bellecourt, Michael J., Mooney, Rachel Anne, Darst, Seth A., Landick, Robert
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5903582/
https://ncbi.nlm.nih.gov/pubmed/29499135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.01.018
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