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RNA polymerase accommodates a pause RNA hairpin by global conformational rearrangements that prolong pausing
Sequence-specific pausing by RNA polymerase (RNAP) during transcription plays crucial and diverse roles in gene expression. In bacteria, RNA structures are thought to fold within the RNA exit channel of the RNAP and can increase pause lifetimes significantly. The biophysical mechanism of pausing is...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5903582/ https://ncbi.nlm.nih.gov/pubmed/29499135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.01.018 |
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