RNA polymerase accommodates a pause RNA hairpin by global conformational rearrangements that prolong pausing

Sequence-specific pausing by RNA polymerase (RNAP) during transcription plays crucial and diverse roles in gene expression. In bacteria, RNA structures are thought to fold within the RNA exit channel of the RNAP and can increase pause lifetimes significantly. The biophysical mechanism of pausing is...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Mol Cell
Autores principales: Kang, Jin Young, Mishanina, Tatiana V., Bellecourt, Michael J., Mooney, Rachel Anne, Darst, Seth A., Landick, Robert
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5903582/
https://ncbi.nlm.nih.gov/pubmed/29499135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.01.018
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares