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RNA polymerase accommodates a pause RNA hairpin by global conformational rearrangements that prolong pausing
Sequence-specific pausing by RNA polymerase (RNAP) during transcription plays crucial and diverse roles in gene expression. In bacteria, RNA structures are thought to fold within the RNA exit channel of the RNAP and can increase pause lifetimes significantly. The biophysical mechanism of pausing is...
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| 發表在: | Mol Cell |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5903582/ https://ncbi.nlm.nih.gov/pubmed/29499135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.01.018 |
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