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RNA polymerase pausing and nascent RNA structure formation are linked through clamp domain movement

The rates of RNA synthesis and nascent RNA folding into biologically active structures are linked via pausing by RNA polymerase (RNAP). Structures that form within the RNA exit channel can increase pausing by interacting with bacterial RNAP or decrease pausing by preventing backtracking. Conversely,...

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Detalhes bibliográficos
Main Authors: Hein, Pyae P., Kolb, Kellie E., Windgassen, Tricia, Bellecourt, Michael J., Darst, Seth A., Mooney, Rachel A., Landick, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156911/
https://ncbi.nlm.nih.gov/pubmed/25108353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2867
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