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Cys-pair reporters detect a constrained trigger loop in a paused RNA polymerase
Transcriptional pausing, which regulates transcript elongation in both prokaryotes and eukaryotes, is thought to involve formation of alternative RNA polymerase conformations in which nucleotide addition is inhibited in part due to restriction of trigger loop (TL) folding. The polymorphous TL must c...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4037917/ https://ncbi.nlm.nih.gov/pubmed/23769674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.05.015 |
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