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Discontinuous movement and conformational change during pausing and termination by T7 RNA polymerase
Time-resolved characterization of T7 RNA polymerase pausing and terminating at a class II termination site has been carried out using site-specifically tethered chemical nucleases. The data indicate that T7RNAP normally moves uniformly down the template as a rigid body. However, at the class II site...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2003
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC291813/ https://ncbi.nlm.nih.gov/pubmed/14657021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg618 |
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