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Mechanism of T7 RNAP Pausing and Termination at the T7 Concatemer Junction: A Local Change in Transcription Bubble Structure Drives a Large Change in Transcription Complex Architecture
The T7RNA polymerase elongation complex (EC) pauses and is destabilized at a unique 8 nt sequence found at the junction of the head to tail concatemers of T7 genomic DNA generated during T7 DNA replication. The paused EC may recruit the T7 DNA processing machinery, which cleaves the concatamerized D...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2254762/ https://ncbi.nlm.nih.gov/pubmed/18166198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.11.090 |
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