Stimulation of the Liver X Receptor Pathway Inhibits HIV-1 Replication via Induction of ATP-Binding Cassette Transporter A1

Cholesterol plays an important role in the HIV life cycle, and infectivity of cholesterol-depleted HIV virions is significantly impaired. Recently, we demonstrated that HIV-1, via its protein Nef, inhibits the activity of the major cellular cholesterol transporter ATP binding cassette transporter A1...

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Bibliografiske detaljer
Main Authors: Morrow, Matthew P., Grant, Angela, Mujawar, Zahedi, Dubrovsky, Larisa, Pushkarsky, Tatiana, Kiselyeva, Yana, Jennelle, Lucas, Mukhamedova, Nigora, Remaley, Alan T., Kashanchi, Fatah, Sviridov, Dmitri, Bukrinsky, Michael
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2010
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917859/
https://ncbi.nlm.nih.gov/pubmed/20479131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.110.065029
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