Small GTPase ARF6 Regulates Endocytic Pathway Leading to Degradation of ATP Binding Cassette Transporter A1

OBJECTIVE: ATP binding cassette transporter A1 (ABCA1) is the principal protein responsible for cellular cholesterol efflux. Abundance and functionality of ABCA1 is regulated both transcriptionally and post-translationally, with endocytosis of ABCA1 being an important element of post-translational r...

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Publicado en:Arterioscler Thromb Vasc Biol
Main Authors: Mukhamedova, Nigora, Hoang, Anh, Cui, Huanhuan L., Carmichael, Irena, Fu, Ying, Bukrinsky, Michael, Sviridov, Dmitri
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5123748/
https://ncbi.nlm.nih.gov/pubmed/27758770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.308418
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