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Two step syntheses of fused quinoxaline-benzodiazepines and bis-benzodiazepines

A two-step solution phase synthesis employing a double UDC (Ugi/Deprotect/Cyclize) strategy has been utilized to obtain fused 6,7,6,6-quinoxalinone-benzodiazepines and 6,7,7,6-bis-benzodiazepines. Optimization of the methodology to produce these tetracyclic scaffolds was enabled by microwave irradia...

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Bibliografiska uppgifter
Huvudupphovsmän: Xu, Zhigang, Dietrich, Justin, Shaw, Arthur Y., Hulme, Christopher
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917818/
https://ncbi.nlm.nih.gov/pubmed/20706616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2010.06.116
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