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Concise Two-Step Solution Phase Syntheses of four novel Dihydroquinazoline scaffolds

Novel two-step solution phase protocols for the synthesis of dihydroquinazolines and fused dihydroquinazoline-benzodiazepine tetracycles are reported. The methodology employs the Ugi reaction to assemble desired diversity and acid treatment enables ring closing transformations. The protocols are fur...

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Detalhes bibliográficos
Main Authors: Dietrich, Justin, Kaiser, Christine, Meurice, Nathalie, Hulme, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897742/
https://ncbi.nlm.nih.gov/pubmed/20625451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2010.05.108
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