FAD Mutations in Amyloid Precursor Protein Do Not Directly Perturb Intracellular Calcium Homeostasis

Disturbances in intracellular calcium homeostasis are likely prominent and causative factors leading to neuronal cell death in Alzheimer's disease (AD). Familial AD (FAD) is early-onset and exhibits autosomal dominant inheritance. FAD-linked mutations have been found in the genes encoding the p...

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Detaylı Bibliyografya
Asıl Yazarlar: Stieren, Emily, Werchan, Walter P., El Ayadi, Amina, Li, Fuzhen, Boehning, Darren
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2010
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916833/
https://ncbi.nlm.nih.gov/pubmed/20700539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011992
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