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Ubiquilin-1 and protein quality control in Alzheimer disease

Single nucleotide polymorphisms in the ubiquilin-1 gene may confer risk for late-onset Alzheimer disease (AD). We have shown previously that ubiquilin-1 functions as a molecular chaperone for the amyloid precursor protein (APP) and that protein levels of ubiquilin-1 are decreased in the brains of AD...

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書誌詳細
主要な著者: El Ayadi, Amina, Stieren, Emily S., Barral, José M., Boehning, Darren
フォーマット: Artigo
言語:Inglês
出版事項: Landes Bioscience 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609125/
https://ncbi.nlm.nih.gov/pubmed/23360761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.23711
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