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Purification and Aggregation of the Amyloid Precursor Protein Intracellular Domain

Amyloid precursor protein (APP) is a type I transmembrane protein associated with the pathogenesis of Alzheimer's disease (AD). APP is characterized by a large extracellular domain and a short cytosolic domain termed the APP intracellular domain (AICD). During maturation through the secretory p...

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Detalhes bibliográficos
Main Authors: El Ayadi, Amina, Stieren, Emily S., Barral, José M., Oberhauser, Andres F., Boehning, Darren
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3478677/
https://ncbi.nlm.nih.gov/pubmed/22952038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/4204
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