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INTRACELLULAR CHOLESTEROL HOMEOSTASIS AND AMYLOID PRECURSOR PROTEIN PROCESSING

Many preclinical and clinical studies have implied a role for cholesterol in the pathogenesis of Alzheimer's disease (AD). In this review we will discuss the movement of intracellular cholesterol and how normal distribution, transport, and export of cholesterol is vital for regulation of the AD...

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Autors principals: Burns, Mark, Rebeck, G. William
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886153/
https://ncbi.nlm.nih.gov/pubmed/20304094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2010.03.004
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