טוען...
Inhibition of Intracellular Cholesterol Transport Alters Presenilin Localization and Amyloid Precursor Protein Processing in Neuronal Cells
Generation of amyloid-β (Aβ) from the amyloid precursor protein (APP) requires proteolytic cleavage by two proteases, β- and γ-secretase. Several lines of evidence suggest a role for cholesterol on secretase activities, although the responsible cellular mechanisms remain unclear. Here we show that a...
שמור ב:
| הוצא לאור ב: | J Neurosci |
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| Main Authors: | , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Society for Neuroscience
2002
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6758870/ https://ncbi.nlm.nih.gov/pubmed/11880497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.22-05-01679.2002 |
| תגים: |
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