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Cell-type-specific processing of the amyloid precursor protein by Presenilin during Drosophila development

The cleavage of proteins within their transmembrane domain by Presenilin (PS) has an important role in different signalling pathways and in Alzheimer's disease. Nevertheless, not much is known about the regulation of PS activity. It has been suggested that substrate recognition by the PS comple...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Loewer, Alexander, Soba, Peter, Beyreuther, Konrad, Paro, Renato, Merdes, Gunter
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1299033/
https://ncbi.nlm.nih.gov/pubmed/15105831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400122
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