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In Vivo Reconstitution of γ-Secretase in Drosophila Results in Substrate Specificity
The intramembrane aspartyl protease γ-secretase plays a fundamental role in several signaling pathways involved in cellular differentiation and has been linked with a variety of human diseases, including Alzheimer's disease. Here, we describe a transgenic Drosophila model for in vivo-reconstitu...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology (ASM)
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2897587/ https://ncbi.nlm.nih.gov/pubmed/20421416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00030-10 |
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