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In Vivo Reconstitution of γ-Secretase in Drosophila Results in Substrate Specificity

The intramembrane aspartyl protease γ-secretase plays a fundamental role in several signaling pathways involved in cellular differentiation and has been linked with a variety of human diseases, including Alzheimer's disease. Here, we describe a transgenic Drosophila model for in vivo-reconstitu...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Stempfle, Denise, Kanwar, Ritu, Loewer, Alexander, Fortini, Mark E., Merdes, Gunter
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897587/
https://ncbi.nlm.nih.gov/pubmed/20421416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00030-10
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