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Cell-type-specific processing of the amyloid precursor protein by Presenilin during Drosophila development

The cleavage of proteins within their transmembrane domain by Presenilin (PS) has an important role in different signalling pathways and in Alzheimer's disease. Nevertheless, not much is known about the regulation of PS activity. It has been suggested that substrate recognition by the PS comple...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Loewer, Alexander, Soba, Peter, Beyreuther, Konrad, Paro, Renato, Merdes, Gunter
פורמט: Artigo
שפה:Inglês
יצא לאור: 2004
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1299033/
https://ncbi.nlm.nih.gov/pubmed/15105831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400122
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