Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2

Cleavage of the amyloid precursor protein (APP) is a crucial event in Alzheimer disease pathogenesis that creates the amyloid-β peptide (Aβ) and liberates the carboxy-terminal APP intracellular domain (AICD) into the cytosol. The interaction of the APP C terminus with the adaptor protein Fe65 mediat...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Radzimanowski, Jens, Simon, Bernd, Sattler, Michael, Beyreuther, Konrad, Sinning, Irmgard, Wild, Klemens
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Scientific Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581855/
https://ncbi.nlm.nih.gov/pubmed/18833287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.188
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados