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Mercury-induced crystallization and SAD phasing of the human Fe65-PTB1 domain

Fe65 is a three-domain neuronal adaptor protein involved in brain development and amyloid precursor protein (APP) signalling. The phosphotyrosine-binding domain 1 (PTB1) of human Fe65 has been cloned, overexpressed, purified and crystallized using the hanging-drop vapour-diffusion method. Native cry...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Radzimanowski, Jens, Ravaud, Stéphanie, Beyreuther, Konrad, Sinning, Irmgard, Wild, Klemens
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376396/
https://ncbi.nlm.nih.gov/pubmed/18453707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S174430910800835X
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