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INTRACELLULAR CHOLESTEROL HOMEOSTASIS AND AMYLOID PRECURSOR PROTEIN PROCESSING

Many preclinical and clinical studies have implied a role for cholesterol in the pathogenesis of Alzheimer's disease (AD). In this review we will discuss the movement of intracellular cholesterol and how normal distribution, transport, and export of cholesterol is vital for regulation of the AD...

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Detalhes bibliográficos
Main Authors: Burns, Mark, Rebeck, G. William
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886153/
https://ncbi.nlm.nih.gov/pubmed/20304094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2010.03.004
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