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Identification of novel peptide substrates for protein farnesyltransferase reveals two substrate classes with distinct sequence selectivities
Prenylation is a post-translational modification essential for the proper localization and function of many proteins. Farnesylation, the attachment of a 15-carbon farnesyl group near the C-terminus of protein substrates, is catalyzed by protein farnesyltransferase (FTase). Farnesylation has received...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2916699/ https://ncbi.nlm.nih.gov/pubmed/19878682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.10.038 |
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