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Evaluation of Protein Farnesyltransferase Substrate Specificity using Synthetic Peptide Libraries
Farnesylation, catalyzed by protein farnesyltransferase (FTase), is an important posttranslational modification guiding cellular localization. Recently predictive models for identifying FTase substrates have been reported. Here we evaluate these models through screening of dansylated-GCaaS peptides,...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2077820/ https://ncbi.nlm.nih.gov/pubmed/17804232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.08.024 |
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