Hedgehog signaling is dispensable for adult hematopoietic stem cell function

The Hedgehog (Hh) signaling pathway is a developmentally conserved regulator of stem cell function. Several reports suggested that Hh signaling is an important regulator of hematopoietic stem cell (HSC) maintenance and differentiation. Here we test this hypothesis in vivo using both gain- and loss-o...

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Detalhes bibliográficos
Main Authors: Gao, Jie, Graves, Stephanie, Koch, Ute, Liu, Suqing, Jankovic, Vladimir, Buonamici, Silvia, Andaloussi, Abdeljabar El, Nimer, Stephen, Kee, Barbara L., Taichman, Russell, Radtke, Freddy, Aifantis, Iannis
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914688/
https://ncbi.nlm.nih.gov/pubmed/19497283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2009.03.015
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