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The Impact of DNA Methylation in Hematopoietic Malignancies

Aberrant DNA methylation is a characteristic feature of cancer including blood malignancies. Mutations in the DNA methylation regulators DNMT3A, TET1/2 and IDH1/2 are recurrent in leukemia and lymphoma. Specific and distinct DNA methylation patterns characterize subtypes of AML and lymphoma. Regulat...

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Detalhes bibliográficos
Publicado no:Trends Cancer
Main Authors: Guillamot, Maria, Cimmino, Luisa, Aifantis, Iannis
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806338/
https://ncbi.nlm.nih.gov/pubmed/27019871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2015.12.006
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