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The Impact of DNA Methylation in Hematopoietic Malignancies
Aberrant DNA methylation is a characteristic feature of cancer including blood malignancies. Mutations in the DNA methylation regulators DNMT3A, TET1/2 and IDH1/2 are recurrent in leukemia and lymphoma. Specific and distinct DNA methylation patterns characterize subtypes of AML and lymphoma. Regulat...
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| Veröffentlicht in: | Trends Cancer |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4806338/ https://ncbi.nlm.nih.gov/pubmed/27019871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2015.12.006 |
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