Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7

Ubiquitination is a posttranslational mechanism that controls diverse cellular processes. We focus here on the ubiquitin ligase Fbw7, a recently identified hematopoietic tumor suppressor that can target for degradation several important oncogenes, including Notch1, c-Myc, and cyclin E. We have gener...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Thompson, Benjamin J., Jankovic, Vladimir, Gao, Jie, Buonamici, Silvia, Vest, Alan, Lee, Jennifer May, Zavadil, Jiri, Nimer, Stephen D., Aifantis, Iannis
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2008
Materias:
Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2413036/
https://ncbi.nlm.nih.gov/pubmed/18474632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20080277
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares