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Control of hematopoietic stem cell quiescence by the E3 ubiquitin ligase Fbw7
Ubiquitination is a posttranslational mechanism that controls diverse cellular processes. We focus here on the ubiquitin ligase Fbw7, a recently identified hematopoietic tumor suppressor that can target for degradation several important oncogenes, including Notch1, c-Myc, and cyclin E. We have gener...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2413036/ https://ncbi.nlm.nih.gov/pubmed/18474632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20080277 |
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