Llwytho...

Bivalent phenethylamines as novel dopamine transporter inhibitors: Evidence for multiple substrate-binding sites in a single transporter

Bivalent ligands—compounds incorporating two receptor-interacting moieties linked by a flexible chain—often exhibit profoundly enhanced binding affinity compared to their monovalent components, implying concurrent binding to multiple sites on the target protein. It is generally assumed that neurotra...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Schmitt, Kyle C, Mamidyala, Sreeman, Biswas, Swati, Dutta, Aloke K, Reith, Maarten EA
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914574/
https://ncbi.nlm.nih.gov/pubmed/20067583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.06583.x
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!