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Nonclassical Pharmacology of the Dopamine Transporter: Atypical Inhibitors, Allosteric Modulators, and Partial Substrates

The dopamine transporter (DAT) is a sodium-coupled symporter protein responsible for modulating the concentration of extraneuronal dopamine in the brain. The DAT is a principle target of various psychostimulant, nootropic, and antidepressant drugs, as well as certain drugs used recreationally, inclu...

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Détails bibliographiques
Auteurs principaux: Schmitt, Kyle C., Rothman, Richard B., Reith, Maarten E. A.
Format: Artigo
Langue:Inglês
Publié: The American Society for Pharmacology and Experimental Therapeutics 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684841/
https://ncbi.nlm.nih.gov/pubmed/23568856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.191056
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