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Spectroscopic and Computational Characterization of Substrate-Bound Mouse Cysteine Dioxygenase: Nature of the Ferrous and Ferric Cysteine Adducts and Mechanistic Implications

Cysteine dioxygenase (CDO) is a mononuclear non-heme Fe-dependent dioxygenase that catalyzes the initial step of oxidative cysteine catabolism. Its active site consists of an Fe(II) ion ligated by three histidine residues from the protein, an interesting variation on the more common 2-His-1-carboxyl...

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Hlavní autoři: Gardner, Jessica D., Pierce, Brad S., Fox, Brian G., Brunold, Thomas C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914100/
https://ncbi.nlm.nih.gov/pubmed/20397631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100189h
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